Detalhe da pesquisa
1.
KaryoCreate: A CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeres.
Cell
; 186(9): 1985-2001.e19, 2023 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37075754
2.
Profound Tissue Specificity in Proliferation Control Underlies Cancer Drivers and Aneuploidy Patterns.
Cell
; 173(2): 499-514.e23, 2018 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29576454
3.
Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome.
Cell
; 155(4): 948-62, 2013 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24183448
4.
A genome-scale screen for synthetic drivers of T cell proliferation.
Nature
; 603(7902): 728-735, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35296855
5.
Persistent telomere damage induces bypass of mitosis and tetraploidy.
Cell
; 141(1): 81-93, 2010 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20371347
6.
The causes and consequences of polyploidy in normal development and cancer.
Annu Rev Cell Dev Biol
; 27: 585-610, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21801013
7.
Somatic 9p24.1 alterations in HPV- head and neck squamous cancer dictate immune microenvironment and anti-PD-1 checkpoint inhibitor activity.
Proc Natl Acad Sci U S A
; 119(47): e2213835119, 2022 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36395141
8.
A genetic interaction analysis identifies cancer drivers that modify EGFR dependency.
Genes Dev
; 31(2): 184-196, 2017 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28167502
9.
Immune evasion in HPV- head and neck precancer-cancer transition is driven by an aneuploid switch involving chromosome 9p loss.
Proc Natl Acad Sci U S A
; 118(19)2021 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33952700
10.
Functional genomics reveals that tumors with activating phosphoinositide 3-kinase mutations are dependent on accelerated protein turnover.
Genes Dev
; 30(24): 2684-2695, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28087713
11.
Spatial PD-L1, immune-cell microenvironment, and genomic copy-number alteration patterns and drivers of invasive-disease transition in prospective oral precancer cohort.
Cancer
; 129(5): 714-727, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36597662
12.
STOP gene Phactr4 is a tumor suppressor.
Proc Natl Acad Sci U S A
; 110(5): E407-14, 2013 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-23319639
13.
A primary melanoma and its asynchronous metastasis highlight the role of BRAF, CDKN2A, and TERT.
J Cutan Pathol
; 42(2): 108-17, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25407517
14.
Proteogenomic insights suggest druggable pathways in endometrial carcinoma.
Cancer Cell
; 41(9): 1586-1605.e15, 2023 09 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37567170
15.
Proteogenomic analysis of cancer aneuploidy and normal tissues reveals divergent modes of gene regulation across cellular pathways.
Elife
; 112022 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36129397
16.
De novo assembly and delivery to mouse cells of a 101 kb functional human gene.
Genetics
; 218(1)2021 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33742653
17.
Not all cancers are created equal: Tissue specificity in cancer genes and pathways.
Curr Opin Cell Biol
; 63: 135-143, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32092639
18.
Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy.
Science
; 355(6322)2017 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28104840
19.
Sources of Error in Mammalian Genetic Screens.
G3 (Bethesda)
; 6(9): 2781-90, 2016 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27402361
20.
Comprehensive identification of host modulators of HIV-1 replication using multiple orthologous RNAi reagents.
Cell Rep
; 9(2): 752-66, 2014 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25373910